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FAQ
Anti-Mouse CD54 Monoclonal Antibody(Biotin Conjugated)
| Product name: | Anti-Mouse CD54 Monoclonal Antibody(Biotin Conjugated) | |
| Catalog: | DL20341F |
|
| Synonyms : | Intercellular adhesion molecule 1,Icam1,MALA-2,MyD10,CD54,Icam-1 | |
| Reactivity: | Mouse | |
| Applications: | FCM | |
| Size: | 50 ug/100 ug | |
| Host: | Rat | |
| Clonality: | ||
| Conjugation: | ||
| Background: | CD54 is a 90 kD immunoglobulin superfamily member also known as ICAM-1 and Ly-47. It is expressed on activated endothelial cells, high endothelial venules (HEV), T and B cells, monocytes/ macrophages, granulocytes, and dendritic cells. CD54 is an important intracellular adhesion molecule that participates in T cell-T cell, T cell-B cell, and T cell-target cell interactions via binding of LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). CD54 has also been shown to be involved in lymphocyte trafficking, making it an important molecule in many immune reactions and inflammation. CD54 is also a receptor for rhinovirus. The YN1/1.7.4 antibody has been reported to block binding of mouse CD54 to LFA-1 and Mac-1, inhibit cell-cell adhesion, and function in antigen presentation to T cells and leukocyte migration to inflammatory tissues. |
|
| Concentration: | 0.5 mg/mL | |
| Buffer: | PBS with 0.05% Proclin300, 1% BSA | |
| Gene_ID: | 15894 | |
| Clone_NO: | YN1/1.7.4 | |
| SwissProt: | P13597 | |
| Isotype: | Rat IgG2b, ? | |
| Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. | |
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