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FAQ
Purified Anti-Mouse CD119 Monoclonal Antibody
| Product name: | Purified Anti-Mouse CD119 Monoclonal Antibody | |
| Catalog: | DL21412F |
|
| Synonyms : | Interferon gamma receptor 1,Ifngr1,IFN-gamma-R1,IFN-gamma-R-alpha,CD119 | |
| Reactivity: | Mouse | |
| Applications: | FCM | |
| Size: | 50 ug/100 ug | |
| Host: | Rat | |
| Clonality: | ||
| Conjugation: | ||
| Background: | CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-??R?? chain. It is a class II cytokine receptor family member that serves as a IFN-??-binding chain associated with the IFN-?? ?? chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-?? induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-?? initiates and regulates a variety of immune responses. |
|
| Concentration: | 0.2 mg/mL | |
| Buffer: | PBS with 0.05% Proclin300 | |
| Gene_ID: | 15979 | |
| Clone_NO: | GR-20 | |
| SwissProt: | P15261 | |
| Isotype: | Rat IgG2a, ? | |
| Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. | |
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