AF/LE Purified Anti-Mouse CD119 Monoclonal Antibody
Product name: | AF/LE Purified Anti-Mouse CD119 Monoclonal Antibody | |
Catalog: | DL21411F |
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Synonyms : | Interferon gamma receptor 1,Ifngr1,IFN-gamma-R1,IFN-gamma-R-alpha,CD119 | |
Reactivity: | Mouse | |
Applications: | FCM | |
Size: | 50 ug/500 ug/1 mg/ | |
Host: | Rat | |
Clonality: | ||
Conjugation: | ||
Background: | CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-??R?? chain. It is a class II cytokine receptor family member that serves as a IFN-??-binding chain associated with the IFN-?? ?? chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-?? induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-?? initiates and regulates a variety of immune responses. |
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Concentration: | 0.2 mg/mL | |
Buffer: | 0.2 um filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg ( < 0.002EU/ug) as Determined by LAL gel clotting assay. | |
Gene_ID: | 15979 | |
Clone_NO: | GR-20 | |
SwissProt: | P15261 | |
Isotype: | Rat IgG2a, ? | |
Storage: | Store at 2~8℃. Do not freeze. |
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