AF/LE Purified Anti-Mouse TCR γ/δ Monoclonal Antibody
Product name: | AF/LE Purified Anti-Mouse TCR γ/δ Monoclonal Antibody | |
Catalog: | DL21563F |
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Synonyms : | TCR-??/??, ??/?? TCR | |
Reactivity: | Mouse | |
Applications: | FCM,IP,IHC | |
Size: | 50 ug/500 ug/1 mg/ | |
Host: | Armenian Hamster | |
Clonality: | ||
Conjugation: | ||
Background: | T cell receptor (TCR) is a heterodimer consisting of an ?? and a ?? chain (TCR ??/??) or a ?? and a ?? chain (TCR ??/??). TCR ??/?? belongs to the immunoglobulin superfamily, involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. The TCR ??/?? associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most ??/?? T cells are CD4-/CD8-, some are CD8+. T cells expressing the TCR ??/?? have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that ??/?? T cells also play a principal role in antigen presentation. Immobilized UC7-13D5 antibody has been reported to activate TCR-??/??-bearing T cells in vitro, and to deplete peripheral TCR-??/??-bearing T cells in vivo. |
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Concentration: | 0.2 mg/mL | |
Buffer: | 0.2 um filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg ( < 0.002EU/ug) as Determined by LAL gel clotting assay. | |
Gene_ID: | 110,066,110,067 | |
Clone_NO: | UC7-13D5 | |
SwissProt: | ||
Isotype: | Armenian Hamster IgG | |
Storage: | Store at 2~8℃. Do not freeze. |
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