Anti-Human CD127/IL-7RA Monoclonal Antibody(PE Conjugated)

Product name:	Anti-Human CD127/IL-7RA Monoclonal Antibody(PE Conjugated)
Catalog:	DL21816F
Synonyms :	Interleukin-7 receptor subunit alpha,IL-7RA,CDw127,CD127,IL-7R??
Reactivity:	Human
Applications:	FCM
Size:	20 Tests/50 Tests/100 Tests/200 Tests
Host:	Mouse
Clonality:
Conjugation:
Background:	CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor ?? chain or IL-7R??. It forms a heterodimer with the common ?? chain (??c or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development.
Concentration:
Buffer:	PBS with 0.05% Proclin300, 1% BSA
Gene_ID:	3575
Clone_NO:	A019D5
SwissProt:	P16871
Isotype:	Mouse IgG1, ?
Storage:	Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.

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DL21816F