AF/LE Purified Anti-Human CD28 Monoclonal Antibody

Product name:	AF/LE Purified Anti-Human CD28 Monoclonal Antibody
Catalog:	DL22135F
Synonyms :	PAS2,MNS,HGpMiX,GYPA,GPSAT
Reactivity:	Human
Applications:	Activ, FCM, IHC, IP
Size:	50 ug/500 ug/1 mg/
Host:	Mouse
Clonality:
Conjugation:
Background:	CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation.
Concentration:	0.2 mg/mL
Buffer:	0.2 um filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg ( < 0.002EU/ug) as Determined by LAL gel clotting assay.
Gene_ID:	940
Clone_NO:	CD28.2
SwissProt:	P10747
Isotype:	Mouse IgG1, ?
Storage:	Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.

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DL22135F