Anti-Human CD28 Monoclonal Antibody(AF488 Conjugated)
Product name: | Anti-Human CD28 Monoclonal Antibody(AF488 Conjugated) | |
Catalog: | DL22144F |
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Synonyms : | PAS2,MNS,HGpMiX,GYPA,GPSAT | |
Reactivity: | Human | |
Applications: | FCM | |
Size: | 20 Tests/50 Tests/100 Tests/200 Tests | |
Host: | Mouse | |
Clonality: | ||
Conjugation: | ||
Background: | CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation. |
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Concentration: | ||
Buffer: | PBS with 0.05% Proclin300, 1% BSA | |
Gene_ID: | 940 | |
Clone_NO: | CD28.2 | |
SwissProt: | P10747 | |
Isotype: | Mouse IgG1, ? | |
Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. |
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