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FAQ
Anti-Human CD40 Monoclonal Antibody(AF488 Conjugated)
| Product name: | Anti-Human CD40 Monoclonal Antibody(AF488 Conjugated) | |
| Catalog: | DL20566F |
|
| Synonyms : | Tumor necrosis factor receptor superfamily member 5,Cd40,B-cell surface antigen CD40,Bp50,CD40L receptor,CD40,Tnfrsf5 | |
| Reactivity: | Human | |
| Applications: | FCM | |
| Size: | 20 Tests/50 Tests/100 Tests/200 Tests | |
| Host: | Mouse | |
| Clonality: | ||
| Conjugation: | ||
| Background: | CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand). The 5C3 antibody has been reported to promote B cell proliferation in the presence of anti-IgM, IL-4 or PMA, partially blocking CD40 binding to CD40L, and B cells rescue from apoptosis. |
|
| Concentration: | ||
| Buffer: | PBS with 0.05% Proclin300, 1% BSA | |
| Gene_ID: | 958 | |
| Clone_NO: | 3A8 | |
| SwissProt: | P25942 | |
| Isotype: | Mouse IgG2a, ? | |
| Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. | |
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