AF/LE Purified Anti-Mouse CD62L Monoclonal Antibody
Product name: | AF/LE Purified Anti-Mouse CD62L Monoclonal Antibody | |
Catalog: | DL20228F |
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Synonyms : | L-selectin,Sell,CD62 antigen-like family member L,LAM-1,LECAM1,Lymph node homing receptor,Ly-22, CD62L,Lnhr,Ly22 | |
Reactivity: | Mouse | |
Applications: | Neut, FCM | |
Size: | 50 ug/500 ug/1 mg/ | |
Host: | Rat | |
Clonality: | ||
Conjugation: | ||
Background: | CD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and na?ve T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte "rolling" on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish na?ve, effector, and memory T cells. CD62L has been reported to interact with CD34, GlyCAM-1, and MAdCAM-1. |
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Concentration: | 0.2 mg/mL | |
Buffer: | 0.2 um filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg ( < 0.002EU/ug) as Determined by LAL gel clotting assay. | |
Gene_ID: | 20343 | |
Clone_NO: | Mel14 | |
SwissProt: | P18337 | |
Isotype: | Rat IgG2a, ? | |
Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. |
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