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Home > FC Antibody

AF/LE Purified Anti-Human CD20 Monoclonal Antibody

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Product name: AF/LE Purified Anti-Human CD20 Monoclonal Antibody
Catalog:

DL22239F

Synonyms : Bp35,Leukocyte surface antigen Leu-16,MS4A1,B-lymphocyte surface antigen B1
Reactivity: Human
Applications: Depletion, FCM, IHC, IP
Size: 50 ug/500 ug/1 mg/
Host: Mouse
Clonality:
Conjugation:
Background:

CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.

Concentration: 0.2 mg/mL
Buffer: 0.2 um filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg ( < 0.002EU/ug) as Determined by LAL gel clotting assay.
Gene_ID: 931
Clone_NO: 2H7
SwissProt: P11836
Isotype: Mouse IgG2b, ?
Storage: Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.

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