Anti-Human CD49d Monoclonal Antibody(PE/Cyanine5.5 Conjugated)
Product name: | Anti-Human CD49d Monoclonal Antibody(PE/Cyanine5.5 Conjugated) | |
Catalog: | DL20600F |
|
Synonyms : | Integrin alpha-4,ITGA4,CD49 antigen-like family member D,Integrin alpha-IV,VLA-4 subunit alpha,CD49d | |
Reactivity: | Human | |
Applications: | FCM | |
Size: | 20 Tests/50 Tests/100 Tests/200 Tests | |
Host: | Mouse | |
Clonality: | ||
Conjugation: | ||
Background: | CD49d is a 150 kD ?? integrin chain known as ??4 integrin or VLA-4 ?? chain. It forms a heterodimer with either integrin ??1 (??4??1, VLA-4) or ??7 (??4??7). CD49d is expressed broadly on T lymphocytes, B lymphocytes, monocytes, thymocytes, eosinophils, basophils, mast cells, NK cells, dendritic cells, and some non-hematopoietic cells, but not on normal red blood cells, platelets or neutrophils. VLA-4 binds to VCAM-1 (CD106) and fibronectin. ??4??7 is the receptor for VCAM-1 and MAdCAM-1. CD49d participates in mononuclear cell trafficking to endothelial sites of inflammation and has roles in cell-cell interactions and cell adhesion to extracellular matrices. CD49d is involved in lymphocyte migration, T cell activation, and hematopoietic stem cell differentiation. CD49d is a marker to isolate pure populations of Treg cells due to its absence on Foxp3+ cells. |
|
Concentration: | ||
Buffer: | PBS with 0.05% Proclin300, 1% BSA | |
Gene_ID: | 3676 | |
Clone_NO: | BU49 | |
SwissProt: | P13612 | |
Isotype: | Mouse IgG1, ? | |
Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. |
Order or get a Quote
We will reply you within 24 hours!