Anti-Human CD47 Monoclonal Antibody(AF488 Conjugated)

Product name:	Anti-Human CD47 Monoclonal Antibody(AF488 Conjugated)
Catalog:	DL20782F
Synonyms :	Leukocyte surface antigen CD47,Cd47,Integrin-associated protein,IAP
Reactivity:	Human
Applications:	FCM
Size:	20 Tests/50 Tests/100 Tests/200 Tests
Host:	Mouse
Clonality:
Conjugation:
Background:	CD47 also known as Rh-associated protein, gp42, integrin-associated protein (IAP), and neurophilin, is a 42-52 kD member of the immunoglobulin superfamily containing a five-pass transmembrane attachment. Two splice variants have been described in the cytoplasmic tail, the shorter form is expressed in bone-marrow-derived cells, endothelial cells, and fibroblasts while the longer form is expressed by neural tissues. CD47 expression is widely distributed in hematopoietic cells including thymocytes, T cells, B cells, monocytes, platelets, and erythrocytes as well as epithelial cells, endothelial cells, fibroblasts, and neural tissues. CD47 functions as an adhesion molecule and thrombospondin receptor and is non-covalently associated with ??3 integrins CD51/CD61, CD41/CD61. Thrombospondin is a ligand for CD47; in the absence of CD47 mice show defects in host defense and ??3 integrin-dependent ligand binding, migration, and cellular activation. CD47 is also part of the Rh complex on erythrocytes.
Concentration:
Buffer:	PBS with 0.05% Proclin300, 1% BSA
Gene_ID:	961
Clone_NO:	CC2C6D4
SwissProt:	Q08722
Isotype:	Mouse IgG1, ?
Storage:	Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.

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DL20782F