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FAQ
EV450 Anti-Human CD45RA Antibody
| Product name: | EV450 Anti-Human CD45RA Antibody | |
| Catalog: | DL22882F |
|
| Synonyms : | Receptor-type tyrosine-protein phosphatase C,Ptprc,L-CA,Ly-5,T200,CD45 | |
| Reactivity: | Human | |
| Applications: | FCM | |
| Size: | 20Tests | |
| Host: | Mouse | |
| Clonality: | ||
| Conjugation: | ||
| Background: | CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/naïve T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines. |
|
| Concentration: | ||
| Buffer: | PBS with 0.05% Proclin300, 1% BSA | |
| Gene_ID: | 5788 | |
| Clone_NO: | ||
| SwissProt: | P08575 | |
| Isotype: | Mouse IgG2b, κ | |
| Storage: | Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. | |
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