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FAQ
EV450 Anti-Rat CD45 Antibody
| Product name: | EV450 Anti-Rat CD45 Antibody | |
| Catalog: | DL22915F |
|
| Synonyms : | Receptor-type tyrosine-protein phosphatase C,Leukocyte common antigen, LCA, T200, Ly-5,Ptprc | |
| Reactivity: | Rat | |
| Applications: | FCM | |
| Size: | 25μg | |
| Host: | Mouse | |
| Clonality: | ||
| Conjugation: | ||
| Background: | CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA). It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets; isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells in vitro. |
|
| Concentration: | 0.5 mg/mL | |
| Buffer: | PBS with 0.05% Proclin300, 1% BSA | |
| Gene_ID: | 19265 | |
| Clone_NO: | ||
| SwissProt: | P04157 | |
| Isotype: | Mouse IgG1, κ | |
| Storage: | Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. | |
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