3 times QC before
delivery.
12-month shelf life.
Strong technical
support
Prompt response
After-sales service guarantee.
| > Cytokine |
| >Signal transduction |
| > Enzyme & Kinase |
| > Metabolic pathway |
| > Tumor immunity |
| > Infection immunity |
| > CD& Adhesion molecule |
| > Neuro science |
| > Developmental science |
FAQ
AF647 Anti-Mouse CD274/PD-L1 Antibody
| Product name: | AF647 Anti-Mouse CD274/PD-L1 Antibody | |
| Catalog: | DL22936F |
|
| Synonyms : | B7-H1, PD-L1,Programmed cell death ligand 1,B7 homolog 1,B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1 | |
| Reactivity: | Mouse | |
| Applications: | FCM | |
| Size: | 25μg | |
| Host: | Rat | |
| Clonality: | ||
| Conjugation: | ||
| Background: | CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-γ, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation and cytokine production. |
|
| Concentration: | 0.5 mg/mL | |
| Buffer: | PBS with 0.05% Proclin300, 1% BSA | |
| Gene_ID: | 60533 | |
| Clone_NO: | ||
| SwissProt: | Q9EP73 | |
| Isotype: | Rat IgG2b, κ | |
| Storage: | Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. | |
Order or get a Quote
We will reply you within 24 hours!
