PE/TR Anti-Mouse CD40 Antibody
Product name: | PE/TR Anti-Mouse CD40 Antibody | |
Catalog: | DL23047F |
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Synonyms : | Tumor necrosis factor receptor superfamily member 5,Cd40,B-cell surface antigen CD40,Bp50,CD40L receptor,CD40,Tnfrsf5 | |
Reactivity: | Mouse | |
Applications: | FCM | |
Size: | 20Tests | |
Host: | Rat | |
Clonality: | ||
Conjugation: | ||
Background: | CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation. |
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Concentration: | ||
Buffer: | PBS with 0.05% Proclin300, 1% BSA | |
Gene_ID: | 21939 | |
Clone_NO: | ||
SwissProt: | P27512 | |
Isotype: | Rat IgG2a, κ | |
Storage: | Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. |
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