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FAQ
PE/TR Anti-Mouse CD40 Antibody
| Product name: | PE/TR Anti-Mouse CD40 Antibody | |
| Catalog: | DL23048F |
|
| Synonyms : | Tumor necrosis factor receptor superfamily member 5,Cd40,B-cell surface antigen CD40,Bp50,CD40L receptor,CD40,Tnfrsf5 | |
| Reactivity: | Mouse | |
| Applications: | FCM | |
| Size: | 25μg | |
| Host: | Rat | |
| Clonality: | ||
| Conjugation: | ||
| Background: | CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation. |
|
| Concentration: | 0.2 mg/mL | |
| Buffer: | PBS with 0.05% Proclin300, 1% BSA | |
| Gene_ID: | 21939 | |
| Clone_NO: | ||
| SwissProt: | P27512 | |
| Isotype: | Rat IgG2a, κ | |
| Storage: | Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. | |
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