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Home > FC Antibody

Anti-Mouse CD274/PD-L1 Monoclonal Antibody(PE Conjugated)

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Product name: Anti-Mouse CD274/PD-L1 Monoclonal Antibody(PE Conjugated)
Catalog:

DL21657F

Synonyms : B7-H1, PD-L1,Programmed cell death ligand 1,B7 homolog 1,B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1
Reactivity: Mouse
Applications: FCM
Size: 20 Tests/50 Tests/100 Tests/200 Tests
Host: Rat
Clonality:
Conjugation:
Background:

CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-?? activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-??, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation and cytokine production.

Concentration:
Buffer: PBS with 0.05% Proclin300, 1% BSA
Gene_ID: 60533
Clone_NO: 10F.9G2
SwissProt: Q9EP73
Isotype: Rat IgG2b, ?
Storage: Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.

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