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| > Infection immunity |
| > CD& Adhesion molecule |
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FAQ
Purified Anti-Human CD47 Monoclonal Antibody
| Product name: | Purified Anti-Human CD47 Monoclonal Antibody | |
| Catalog: | DL20772F |
|
| Synonyms : | Leukocyte surface antigen CD47,Cd47,Integrin-associated protein,IAP | |
| Reactivity: | Human | |
| Applications: | FCM | |
| Size: | 25 ug/100 ug | |
| Host: | Mouse | |
| Clonality: | ||
| Conjugation: | ||
| Background: | CD47 also known as Rh-associated protein, gp42, integrin-associated protein (IAP), and neurophilin, is a 42-52 kD member of the immunoglobulin superfamily containing a five-pass transmembrane attachment. Two splice variants have been described in the cytoplasmic tail, the shorter form is expressed in bone-marrow-derived cells, endothelial cells, and fibroblasts while the longer form is expressed by neural tissues. CD47 expression is widely distributed in hematopoietic cells including thymocytes, T cells, B cells, monocytes, platelets, and erythrocytes as well as epithelial cells, endothelial cells, fibroblasts, and neural tissues. CD47 functions as an adhesion molecule and thrombospondin receptor and is non-covalently associated with ??3 integrins CD51/CD61, CD41/CD61. Thrombospondin is a ligand for CD47; in the absence of CD47 mice show defects in host defense and ??3 integrin-dependent ligand binding, migration, and cellular activation. CD47 is also part of the Rh complex on erythrocytes. |
|
| Concentration: | 0.2 mg/mL | |
| Buffer: | PBS with 0.05% Proclin300 | |
| Gene_ID: | 961 | |
| Clone_NO: | CC2C6D4 | |
| SwissProt: | Q08722 | |
| Isotype: | Mouse IgG1, ? | |
| Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. | |
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