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FAQ
Anti-Mouse FcεRIα Monoclonal Antibody(APC Conjugated)
| Product name: | Anti-Mouse FcεRIα Monoclonal Antibody(APC Conjugated) | |
| Catalog: | DL22054F |
|
| Synonyms : | High affinity immunoglobulin epsilon receptor subunit alpha,Fc-epsilon RI-alpha,FcERI,Fcer1a | |
| Reactivity: | Mouse | |
| Applications: | FCM | |
| Size: | 50 Tests/100 Tests/200 Tests/500 Tests | |
| Host: | Armenian Hamster | |
| Clonality: | ||
| Conjugation: | ||
| Background: | FcεRIα is a transmembrane protein belonging to the Ig superfamily. FcεRIα forms a tetrameric complex with one ?? and two ??-subunits. The Fc??RI complex plays an important role in triggering IgE-mediated allergic reactions. It is abundantly expressed on mast and basophils and up-regulated by the presence of IgE. Following stimulation via FcεRIα, mast cells and basophils release bioactive chemical mediators such as histamine, resulting in the initiation of allergic reactions. Cross linking of the high-affinity receptor for IgE on tissue mast cells triggers immediate hypersensitivity with local symptoms. The MAR-1 monoclonal antibody reacts with the FcεRIα subunit. |
|
| Concentration: | ||
| Buffer: | PBS with 0.05% Proclin300, 1% BSA | |
| Gene_ID: | 14125 | |
| Clone_NO: | 1-Mar | |
| SwissProt: | P20489 | |
| Isotype: | Armenian Hamster IgG | |
| Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. | |
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