Purified Anti-Human CD40 Monoclonal Antibody
Product name: | Purified Anti-Human CD40 Monoclonal Antibody | |
Catalog: | DL20556F |
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Synonyms : | Tumor necrosis factor receptor superfamily member 5,Cd40,B-cell surface antigen CD40,Bp50,CD40L receptor,CD40,Tnfrsf5 | |
Reactivity: | Human | |
Applications: | FCM | |
Size: | 25 ug/100 ug | |
Host: | Mouse | |
Clonality: | ||
Conjugation: | ||
Background: | CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand). The 5C3 antibody has been reported to promote B cell proliferation in the presence of anti-IgM, IL-4 or PMA, partially blocking CD40 binding to CD40L, and B cells rescue from apoptosis. |
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Concentration: | 0.2 mg/mL | |
Buffer: | PBS with 0.05% Proclin300 | |
Gene_ID: | 958 | |
Clone_NO: | 3A8 | |
SwissProt: | P25942 | |
Isotype: | Mouse IgG2a, ? | |
Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. |
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