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Home > FC Antibody

Purified Anti-Mouse CD279/PD-1 Monoclonal Antibody

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Product name: Purified Anti-Mouse CD279/PD-1 Monoclonal Antibody
Catalog:

DL21638F

Synonyms : PD-1, Programmed Death-1
Reactivity: Mouse
Applications: FCM, WB, IHC, IF
Size: 50 ug/100 ug
Host: Rat
Clonality:
Conjugation:
Background:

CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.

Concentration: 0.2 mg/mL
Buffer: PBS with 0.05% Proclin300
Gene_ID: 18566
Clone_NO: 29F.1A12
SwissProt: Q02242
Isotype: Rat IgG2a, ?
Storage: Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.

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