Purified Anti-Mouse CD279/PD-1 Monoclonal Antibody
Product name: | Purified Anti-Mouse CD279/PD-1 Monoclonal Antibody | |
Catalog: | DL21638F |
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Synonyms : | PD-1, Programmed Death-1 | |
Reactivity: | Mouse | |
Applications: | FCM, WB, IHC, IF | |
Size: | 50 ug/100 ug | |
Host: | Rat | |
Clonality: | ||
Conjugation: | ||
Background: | CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts. |
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Concentration: | 0.2 mg/mL | |
Buffer: | PBS with 0.05% Proclin300 | |
Gene_ID: | 18566 | |
Clone_NO: | 29F.1A12 | |
SwissProt: | Q02242 | |
Isotype: | Rat IgG2a, ? | |
Storage: | Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze. |
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