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The HIV-1 envelope protein gp120 impairs B cell proliferation by inducing TGF-β1 production and FcRL4 expression
The humoral immune response after acute infection with HIV-1 is delayed and ineffective The HIV-1 envelope protein gp120 binds to and signals through integrin α4β7 on T cells We found that gp120 also bound to and s ...[Read More]
Ki-67 Protein (Ki67P)
other names：MKI67; KIA; Ki-67; Antigen Identified By Monoclonal Antibody Ki-67 The Ki-67 protein is a cellular marker for proliferation It is strictly associated with cell proliferation During interphase, the Ki-67 antigen can be ...[Read More]
Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP)
Nicotinic acid adenine dinucleotide phosphate, also known as NAADP+, is a nucleotide very similar to NADP, with the nicotinamide replaced with a niacin molecule NAADP is one of the most potent Calcium signalling messenger molecu ...[Read More]
Agrin (AGRN)
Agrin is a large proteoglycan whose best characterised role is in the development of the neuromuscular junction during embryogenesis Agrin is named based on its involvement in the aggregation of acetylcholine receptors during syn ...[Read More]
Enolase, Non Neuronal (NNE)
other names：ENO1; ENO1L1; MBP-1; MPB1; PPH; Alpha Enolase Enolase 1, more commonly known asα-enolase, is a glycolytic enzyme expressed in most tissues, one of the isozymes of enolase It is a homodimer composed of 2 alpha ...[Read More]
Interleukin 4 Induced Protein 1 (IL4I1)
IL4I1 shares the limited similarity with L-amino acid oxidase, and contains the conserved key amino acid residues thought to be involved in catalysis and binding of the flavin adenine dinucleotide cofactor The expression of this ...[Read More]
Adrenocorticotropic Hormone (ACTH)
ACTH (Adrenocorticotropic hormone） or corticotropin is a 39-amino acid peptide hormone (MW=4500) secreted by the pituitary to regulate the production of steroid hormones by the adrenal cortex ACTH secretion from the anterior pitu ...[Read More]
Transforming, Acidic Coiled-Coil Containing Protein 1 (TACC1)
Introduction of TACC1 into stable cell lines resulted in morphologic changes consistent with a transformed phenotype and in anchorage-independent growth However, it is speculated that it may represent a breast cancer candidate gen ...[Read More]
