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Anti-Double Stranded DNA Antibody (Anti-dsDNA)
Antibodies against dsDNA are found during active phases of SLE The amount of the serum concentration is positively correlated with the severity of the disease Thus, detection of these autoantibodies is important for the diagnos ...[Read More]
Apelin 17 (AP17)
Apelin gene encodes a pre-proprotein of 77 amino acids, with a signal peptide in the N-terminal region After translocation into the endoplasmic reticulum and cleavage of the signal peptide, the proprotein of 55 amino acids may ...[Read More]
Myeloid Differentiation Factor 88 (MyD88)
Myeloid differentiation factor 88 (MyD88) is a key adaptor protein that MyD88 is a common adaptor molecule required for signaling mediated by TLRs When the receptors are activated, cells bearing TLRs produce various proinflammato ...[Read More]
Adaptor Related Protein Complex 2 Sigma 1 (AP2s1)
One of two major clathrin-associated adaptor complexes, AP-2, is a heterotetramer which is associated with the plasma membrane This complex is composed of two large chains, a medium chain, and a small chain AP17 is the 17-kD c ...[Read More]
Neurogranin (NRGN)
Neurogranin is a calmodulin-binding protein expressed exclusively in the brain, particularly in dendritic spines, and participating in the protein kinase C signaling pathway Neurogranin is the main postsynaptic protein regulating th ...[Read More]
Calbindin 3 (CALB3)
other names:S100G; CABP9K; CABP1; Calbindin-D9K; S100 Calcium Binding Protein G; Vitamin D-Dependent Calcium-Binding ProteinCalbindin D9K, the vitamin D-dependent calcium-binding protein (CaBP9K), was first described in rat intestine The ...[Read More]
Telomerase Reverse Transcriptase (TERT)
Telomerase reverse transcriptase is a catalytic subunit of the enzyme telomerase Its absence (usually as a result of a chromosomal mutation) is associated with the disorder Cri du chat Telomerase is a ribonucleoprotein polymerase ...[Read More]
Programmed Cell Death Protein 1 Ligand 1 (PDCD1LG1)
CD274 (Cluster of Differentiation 274) also known as PD-L1 (Programed Death Ligand-1) or B7-H1 is a protein,PD-L1 binds to its receptor, PD-1, found on activated T cells, B cells, and myeloid cells, to modulate activation or in ...[Read More]
