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Significance of determination of C-reactive protein (CRP) levels

C-reactive protein (CRP) is a general marker of infection and inflammation. CRP elevations are mostly caused by infections and chronic diseases. It will be detected within a few hours after inflammation. Therefore, the increase in CRP level means that there is inflammation, and when the inflammation disappears, CRP levels will fall back to normal levels. However, the site or cause of inflammation cannot be determined.
So, what is the significance of determining CRP levels?
1. Determination of CRP levels can determine the severity of the infection
When diagnosing inflammatory diseases, especially in the early stage of the disease, the CRP level changes very sensitively, and its increase is positively correlated with the severity of the disease, and it can quickly drop to the normal value after the pathogen is eliminated. In many diseases, when the inflammatory symptoms are not obvious, the significantly increased CRP (>100mg/L) can tell us that there is a serious bacterial or fungal infection in the body, so that it can be diagnosed and treated as soon as possible. For example, CRP is often used to assess the severity of acute pancreatitis. When CRP is higher than 250mg/L, it indicates extensive necrotizing pancreatitis.
2. Determining CRP levels can identify types of respiratory infections
In diagnosing diseases that distinguish bacterial and viral infections of the respiratory tract, we can distinguish between the two based on physical examination in combination with CRP levels. In bacterial infections, CRP levels increase; and in viral infections, CRP does not increase or slightly increases. Therefore, CRP values can help doctors identify the type of respiratory infections and give targeted drugs and treatments.
3. The determination of CRP level can be used for the rapid diagnosis of sepsis and other diseases
CRP in the body rises rapidly in sepsis, and it takes at least 48 hours to rely on blood culture. The CRP value in bacterial meningitis can also increase rapidly, while the increase in other types of meningitis is not obvious.
4. Determining CRP levels can prevent cardiovascular disease
Studies have shown that CRP is directly involved in cardiovascular diseases such as atherosclerosis, and is the most powerful predictor and risk factor for cardiovascular diseases. A survey in the United States showed that women with high levels of inflammation (CRP>3mg/L) are at twice the risk of dying from myocardial infarction and stroke than those with hypercholesterolemia. Therefore, some experts suggest that regular CRP tests can detect the potential risk of heart disease as early as possible. If the test finds an increase in CRP, one should be vigilant. Diet control, proper weight loss, smoking cessation and exercise can significantly reduce the level of CRP.
All in all, measuring CRP levels is of great significance. At the same time, rapid detection of CRP content is also very important, ELISA test method can quickly and accurately detect CRP content. At present, Wuxi Donglin Sci & Tech Development Co.,Ltd. has developed a variety of high-quality CRP Elisa products. For more information, you can directly contact our professionals or visit our website:
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