Dopamine (DA)
A study at the university of Virginia found that neurons in the brain that produce DA (dopamine) can directly control the brain's rhythm center, also known as the body clock. The body clock is associated with eating, metabolism, waking and resting, and is a key factor in the body's ability to deal with jet lag and shift work. The results are published in Current Biology.
Professor Ali Deniz Guler, of the university of Virginia, said: "this finding could lead to finding neurons associated with the center of the rhythm, and potentially to developing drugs that target those neurons, further intervening with negative emotions or more severe symptoms caused by jet lag or shift work. "Modern people's body is under too much pressure, such as changing work plan at any time according to the flight, not resting according to the natural law, not eating on time and so on.
These external conditions lead to the body's natural rhythm imbalance, the body can no longer be separated from the clear day and night. In the long run, it can lead to depression, obesity, cardiovascular disease and even cancer. Scientists have worked for decades to help the body clock adapt to the diverse work, diet and time zone flight of modern life. Finding the relationship between DA-producing neurons and the pacemaker centers can help us with targeted therapy, ease the symptoms of jet lag and night shift workers, and potentially help insomniacs. Disorders of sleep disorders and circadian rhythms due to DA secretion affect the brain and other organs and can worsen the course of Parkinson's disease, depression, bipolar disorder, and adhd. In their study, the scientists used two types of mice - the normal group and the DA-signaling abnormal group.
By having two groups of animals switch from day to night every six hours (mimicking the time difference), it was found that the DA-signaling abnormality group took longer to adapt to the six-hour shift. This suggests a link between DA-producing neurons and the heart of the rhythm. It also suggests that when we engage in beneficial activities like eating, we unconsciously influence our biorhythm.
At present, DLDEVELOP co. LTD has developed corresponding DA Elisa products. To get more information, you could contact our professional staff directly or directly to our website:
https://dldevelop.com/Research-reagent/dl-da-ge.html
https://www.dldevelop.com/uploadfile/data/DL-DA-Ge.pdf
Professor Ali Deniz Guler, of the university of Virginia, said: "this finding could lead to finding neurons associated with the center of the rhythm, and potentially to developing drugs that target those neurons, further intervening with negative emotions or more severe symptoms caused by jet lag or shift work. "Modern people's body is under too much pressure, such as changing work plan at any time according to the flight, not resting according to the natural law, not eating on time and so on.
These external conditions lead to the body's natural rhythm imbalance, the body can no longer be separated from the clear day and night. In the long run, it can lead to depression, obesity, cardiovascular disease and even cancer. Scientists have worked for decades to help the body clock adapt to the diverse work, diet and time zone flight of modern life. Finding the relationship between DA-producing neurons and the pacemaker centers can help us with targeted therapy, ease the symptoms of jet lag and night shift workers, and potentially help insomniacs. Disorders of sleep disorders and circadian rhythms due to DA secretion affect the brain and other organs and can worsen the course of Parkinson's disease, depression, bipolar disorder, and adhd. In their study, the scientists used two types of mice - the normal group and the DA-signaling abnormal group.
By having two groups of animals switch from day to night every six hours (mimicking the time difference), it was found that the DA-signaling abnormality group took longer to adapt to the six-hour shift. This suggests a link between DA-producing neurons and the heart of the rhythm. It also suggests that when we engage in beneficial activities like eating, we unconsciously influence our biorhythm.
At present, DLDEVELOP co. LTD has developed corresponding DA Elisa products. To get more information, you could contact our professional staff directly or directly to our website:
https://dldevelop.com/Research-reagent/dl-da-ge.html
https://www.dldevelop.com/uploadfile/data/DL-DA-Ge.pdf
