Human Nuclear Receptor Coactivator 3 (NCOA3)
NCOA3, a member of the p160 protein family, is a nuclear receptor coactivator .
NCOA3 binds to a variety of transcription factors, including nuclear receptors, and ACTS as a bridge in the regulation of transcription factors on target genes . Meanwhile, NCOA3 also has histone acetyltransferase activity, which can promote gene transcription.NCOA3 plays an important role in many physiological processes, such as somatic cell growth, female reproductive function, breast tissue development, and stem cell pluripotency maintenance . The overexpression of NCOA3 in many tumor cells promoted the occurrence of many pathological states.NCOA3 inside transcriptional activation activity has been translated in many decoration, such as phosphorylation ,methylation and acetylation of wood grain, ubiquitin, etc, these modifications affect the stability of the protein, can make it through the Fan Su depend on the way or not ubiquitin depend on the way to degrade . Moreover, NCOA3 shuttles between the nucleus and cytoplasm, regulating its subcellular localization and function.
At present, DLDEVELOP co. LTD has developed corresponding NCOA3 Elisa products. To get more information, you could contact our professional staff directly or directly to our website:
https://dldevelop.com/Research-reagent/dl-ncoa3-hu.html
https://dldevelop.com/Research-reagent/dl-ncoa3-ra.html
NCOA3 binds to a variety of transcription factors, including nuclear receptors, and ACTS as a bridge in the regulation of transcription factors on target genes . Meanwhile, NCOA3 also has histone acetyltransferase activity, which can promote gene transcription.NCOA3 plays an important role in many physiological processes, such as somatic cell growth, female reproductive function, breast tissue development, and stem cell pluripotency maintenance . The overexpression of NCOA3 in many tumor cells promoted the occurrence of many pathological states.NCOA3 inside transcriptional activation activity has been translated in many decoration, such as phosphorylation ,methylation and acetylation of wood grain, ubiquitin, etc, these modifications affect the stability of the protein, can make it through the Fan Su depend on the way or not ubiquitin depend on the way to degrade . Moreover, NCOA3 shuttles between the nucleus and cytoplasm, regulating its subcellular localization and function.
At present, DLDEVELOP co. LTD has developed corresponding NCOA3 Elisa products. To get more information, you could contact our professional staff directly or directly to our website:
https://dldevelop.com/Research-reagent/dl-ncoa3-hu.html
https://dldevelop.com/Research-reagent/dl-ncoa3-ra.html
